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MMP13 — SPP1

Text-mined interactions from Literome

Lai et al., Circ Res 2006 : To better understand its role in vascular remodeling, we assessed how OPN controls metalloproteinase ( MMP ) activation in aortic adventitial myofibroblasts ( AMFs ) and A7r5 vascular smooth muscle cells ( VSMCs )
Castellano et al., Clin Cancer Res 2008 (Disease Progression...) : Osteopontin (OPN) , which activates matrix metalloproteinases ( MMP ) , is considered a prognostic biomarker in several cancers ... `` In silico '' and experimental approaches were used to determine whether OPN mediated MMP activation may be a signal of prostate cancer progression
Matsui et al., Arthritis Rheum 2009 (Arthritis, Experimental...) : OPN deficiency also led to the induction of matrix metalloproteinase 13 (MMP-13) , which degrades a major component of the cartilage matrix protein type II collagen
Buommino et al., Arch Dermatol Res 2012 (Psoriasis) : Interestingly, MMP-9 expression can be enhanced also by osteopontin (OPN) , a glycosylated protein whose levels are increased in skin and peripheral blood mononuclear cells ( PBMC ) of psoriasis patients
Xu et al., Rheumatol Int 2013 (Osteoarthritis, Knee) : We found OPN leads to elevated expression of MMP-13 ( both at gene level and protein level ), and phospho-OPN had a more obvious upregulation effect on MMP-13 expression than nonphospho-OPN
Tan et al., Lab Invest 2013 (Fibrosis...) : Moreover, MMP-9 inhibition caused a significant reduction in MMP-9 cleaved osteopontin and macrophage infiltration in UUO kidney