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GRB2 — TYR

Text-mined interactions from Literome

Ho et al., Blood 2002 : Studies with a TEL-JAK2 ( 5-19 ) Tyr314Phe mutant support a role for Tyr314 in Grb2 recruitment, because Grb2 association with TEL-JAK2 ( 5-19 ) Tyr314Phe is significantly reduced
Lamalice et al., J Biol Chem 2006 : We also report that the SH2 domain containing adapter molecule Nck, but not Grb2 , is recruited to VEGFR-2 in a p-Tyr1214 dependent manner and that it associates with Fyn
Wu et al., J Biol Chem 2011 : In turn, Rab13 associates with Grb2 , targeting Syx and RhoA to Tyr ( 1175 ) -phosphorylated VEGFR2 at the leading edge
Arvidsson et al., Mol Cell Biol 1994 : Tyr-716 in the platelet derived growth factor beta-receptor kinase insert is involved in GRB2 binding and Ras activation ... Here we show that Tyr-716 , a novel autophosphorylation site in the PDGF beta-receptor kinase insert, mediates direct binding of GRB2 in vitro and in vivo
Schlaepfer et al., Mol Cell Biol 1998 : In vitro, FAK directly phosphorylated Shc Tyr-317 to promote Grb2 binding, and in vivo Grb2 binding to Shc was observed in herbimycin A-treated fibroblasts after FN stimulation