◀ Back to MAPK1
BDKRB2 — MAPK1
Text-mined interactions from Literome
Searovic et al., J Cell Biochem 2009
:
We showed that the anti-tumoral effect of tamoxifen/all-trans retinoic acid is beneficial in MCF-7 breast cancer cells grown in a bradykinin-pro-mitogenic environment, an effect that might be, at least in part, through the
MAPK pathway and
B2-bradykinin receptor inhibition
Blaes et al., American journal of physiology. Renal physiology 2012
(Diabetes Mellitus, Experimental...) :
B2R activation
inhibited TGF-ß- and EGF induced
Erk1/2 , Smad2/3, Akt S473, and EGFR phosphorylation
Fields et al., Journal of neuroinflammation 2012
(Inflammation) :
Inhibiting extracellular regulated kinase
(ERK)1/2 activation
blocked IL-1ß induced
BDKRB2 mRNA expression while increasing COX-2 expression