◀ Back to CCR5
CCL8 — CCR5
Pathways - manually collected, often from reviews:
-
KEGG Chemokine signaling pathway:
CCL1/CCL11/CCL13/CCL14/CCL15/CCL16/CCL17/CCL18/CCL19/CCL2/CCL20/CCL21/CCL22/CCL23/CCL24/CCL25/CCL26/CCL27/CCL28/CCL3/CCL3L1/CCL3L3/CCL4/CCL4L1/CCL4L2/CCL5/CCL7/CCL8/CX3CL1/CXCL1/CXCL10/CXCL11/CXCL12/CXCL13/CXCL14/CXCL16/CXCL2/CXCL3/CXCL5/CXCL6/CXCL9/IL8/PF4/PF4V1/PPBP/XCL1/XCL2
→
CCR1/CCR10/CCR2/CCR3/CCR4/CCR5/CCR6/CCR7/CCR8/CCR9/CX3CR1/CXCR1/CXCR2/CXCR3/CXCR4/CXCR5/CXCR6/XCR1
(protein-protein, activation)
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
-
IRef Dip Interaction:
CCL8
—
CCR5
(physical association, biochemical)
Blanpain et al., Blood 1999*
-
IRef Dip Interaction:
CCL8
—
CCR5
(physical association, biochemical)
Gong et al., J Biol Chem 1998*
-
IRef Hprd Interaction:
CCL8
—
CCR5
(in vivo)
Blanpain et al., Blood 1999*, Gong et al., J Biol Chem 1998*
-
IRef Innatedb Interaction:
CCL8
—
CCR5
(unknown, -)
Blanpain et al., Blood 1999*
-
IRef Ophid Interaction:
CCL8
—
CCR5
(aggregation, confirmational text mining)
Blanpain et al., Blood 1999*
-
IRef Ophid Interaction:
CCL8
—
CCR5
(aggregation, interologs mapping)
Brown et al., Bioinformatics 2005
Text-mined interactions from Literome
Gong et al., J Biol Chem 1998
:
Monocyte chemotactic protein-2 activates
CCR5 and blocks CD4/CCR5 mediated HIV-1 entry/replication
Ruffing et al., Cell Immunol 1998
:
Furthermore,
MCP-2 inhibited the binding of the M-tropic HIV-1 gp120 envelope glycoprotein to
CCR5 and HIV-1 infection of peripheral blood mononuclear cells