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EPHB2 — FURIN
Text-mined interactions from Literome
Tellier et al., Mol Cell Biol 2007
:
Pharmacological and molecular inhibitors of MMPs ( batimastat ),
furin ( alpha1-PDX inhibitor transfected SMC ), MT1-MMP ( SMC overexpressing a catalytically inactive MT1-MMP ), MMP2 ( fibroblasts from MMP2 ( -/- ) mice ), and small interfering RNA ( siRNA ) strategies ( siRNAs targeting furin, MT1-MMP, MMP2, and nSMase )
resulted in near-complete inhibition of the activation of nSMase, sphingosine kinase-1, and
ERK1/2 and of subsequent DNA synthesis
Poli et al., Haematologica 2010
(Hemochromatosis...) :
The data indicate that transferrin receptor 2 and HFE are involved in holotransferrin dependent signaling for the regulation of
furin which
involved Erk phosphorylation