Gene interactions and pathways from curated databases and text-mining

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AKT1 — PML

Text-mined interactions from Literome

Giorgi et al., Science 2010 (Calcium Signaling) : Pml was essential for Akt- and PP2a dependent modulation of IP ( 3 ) R phosphorylation and in turn for IP ( 3 ) R-mediated Ca ( 2+ ) release from ER
Rokudai et al., Proc Natl Acad Sci U S A 2013 (Leukemia, Promyelocytic, Acute) : As a result of PML mediated suppression of Akt , the increased PML-MOZ interaction enhances p21 expression and induces p53 dependent premature senescence upon forced PML expression