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ABL1 — IL3
Text-mined interactions from Literome
Horita et al., J Exp Med 2000
(Blast Crisis...) :
Here, we show that the
interleukin 3-independent expression of the antiapoptotic protein, Bcl-xL, is
induced by
Bcr-Abl through activation of signal transducer and activator of transcription ( Stat ) 5
Li et al., Blood 2001
(Cell Transformation, Neoplastic...) :
Interleukin 3 and granulocyte-macrophage colony stimulating factor are not
required for induction of chronic myeloid leukemia-like myeloproliferative disease in mice by
BCR/ABL
Jiang et al., Blood 2002
(Cell Transformation, Neoplastic...) :
These findings provide new evidence that
IL-3 production is a rapid, sustained, and biologically relevant
consequence of
BCR-ABL expression in primitive hematopoietic cells with multilineage leukemogenic activity
Park et al., Exp Hematol 2010
(Blast Crisis...) :
In addition,
interleukin-3 induced
c-ABL phosphorylation and constitutively enhanced extracellular signal regulated kinase phosphorylation was not inhibited by imatinib in SNUCML-02
Matsuguchi et al., J Biol Chem 1994
(Leukemia, Megakaryoblastic, Acute) :
Shc phosphorylation in myeloid cells is regulated by granulocyte macrophage colony stimulating factor,
interleukin-3 , and steel factor and is constitutively
increased by
p210BCR/ABL
Zhang et al., Blood 1998
(Cell Transformation, Neoplastic...) :
Bcr-Abl efficiently
induces a myeloproliferative disease and production of excess
interleukin-3 and granulocyte-macrophage colony stimulating factor in mice : a novel model for chronic myelogenous leukemia