Castro-Obregón et al., J Biol Chem 2004
(MAP Kinase Signaling System) :
The activation of the protein kinases Raf-1, MEK2, and ERK2 is essential for this form of nonapoptotic pcd , leading to the phosphorylation of the orphan nuclear receptor Nur77
Kim et al., Exp Mol Med 2007
(Calcium Signaling) :
PhS1P also activated ERK and p38 kinase, and these activations by PhS1P were inhibited by PTX