We have a suspicion that you are an automated web bot software, not a real user. To keep our site fast for other users, we have slowed down this page. The slowdown will gradually disappear. If you think this is a mistake, please contact us at genome-www@soe.ucsc.edu. Also note that all data for hgGeneGraph can be obtained through our public MySQL server and all our software source code is available and can be installed locally onto your own computer. If you are unsure how to use these resources, do not hesitate to contact us.
UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

◀ Back to IL6

IL6 — NPY

Text-mined interactions from Literome

Straub et al., J Neurochem 2000 (Synaptic Transmission) : Under these conditions, NPY dose-dependently inhibited IL-6 secretion with a maximum effect at 10 ( -10 ) M : ( p = 0.012 ) and 10 ( -9 ) M : ( p < 0.001 )
Hernanz et al., Regul Pept 2003 (Arthritis, Rheumatoid...) : In the present study, we have investigated the in vitro effect of calcitonin related peptide ( CGRP ), neuropeptide Y (NPY) , substance P ( SP ) and vasoactive intestinal peptide (VIP) at concentrations of 10 ( -8 ), 10 ( -9 ) and 10 ( -10 ) M on the production of different proinflammatory cytokines or chemokines such as IL-1beta, IL-6 and TNFalpha by peripheral whole blood cells from patients with rheumatoid arthritis, as well as from osteoarthritis patients studied as a control group without immunoinflammatory background
Singer et al., PloS one 2013 (Inflammation...) : NPY receptor inhibition promoted DC maturation and the production of IL-6 and TNFa suggesting an anti-inflammatory function for NPY signaling in DCs
Zhou et al., J Neuroimmunol 2013 (MAP Kinase Signaling System) : In the present work, we have evaluated the effects of NPY on the release of TNF-a, IL-1ß, IL-6 and HMGB1 mediators in peritoneal macrophages ... Our results demonstrate for the first time that NPY can directly induce active HMGB1 release and cytoplasmic translocation, while the production of TNF-a, IL-1ß and IL-6 is not affected
Pazos et al., PloS one 2013 : Il6 deficiency during this stage up-regulated Npy and Agrp expression, while restoring Pomc mRNA levels to virgin values
Hernanz et al., J Neuroimmunol 1996 : Differential effects of gastrin releasing peptide, neuropeptide Y , somatostatin and vasoactive intestinal peptide on interleukin-1 beta, interleukin-6 and tumor necrosis factor-alpha production by whole blood cells from healthy young and old subjects ... In the present study, we have investigated the effect in vitro of gastrin releasing peptide ( GRP, 10 ( -10 ) M ), neuropeptide Y ( NPY, 10 ( -10 ) M ), somatostatin ( 10 ( -10 ) M ) and vasoactive intestinal peptide ( VIP, 10 ( -9 ) M ) on the production of IL-1 beta, IL-6 and TNF alpha by peripheral whole blood cells from healthy young and old people ... In addition, the production of IL-6 was enhanced by GRP, NPY and VIP in young and old people