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NPY6R — PLCG2
Text-mined interactions from Literome
Ohmori et al., Biochemistry 2001
:
Furthermore, the Src family kinase inhibitor
PP2 inhibited WGA induced platelet aggregation, Ca ( 2+ ) mobilization, and
PLC-gamma 2 tyrosine phosphorylation
Polanowska-Grabowska et al., Arterioscler Thromb Vasc Biol 2003
:
PP2 , although having no effect on RGD peptide binding to CRP, completely
blocked aggregation and tyrosine phosphorylation of Syk and
phospholipase Cgamma2 ( PLCgamma2 ) ... Although
PP2 prevented activation of Syk and
PLCgamma2 in collagen-adherent platelets, tyrosine phosphorylation of several unidentified protein bands persisted, as did autophosphorylation of pp125FAK
Guidetti et al., Journal of thrombosis and haemostasis : JTH 2009
:
However, when phosphorylation of
PLCgamma2 was
blocked by the Src kinase inhibitor
PP2 , prevention of Rac1 activation significantly reduced PLCgamma2 activation, GTP-Rap1b accumulation, and alpha ( IIb ) beta3 stimulation