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ATR — CCNB1

Text-mined interactions from Literome

Deming et al., J Biol Chem 2002 (Chromosome Aberrations) : Here we report that induction of this checkpoint with ICRF-193, a topoisomerase II catalytic inhibitor that does not cause DNA damage, was associated with an ATR dependent inhibition of polo-like kinase 1 (Plk1) kinase activity and a decrease in cyclin B1 phosphorylation
Yazlovitskaya et al., Anticancer Res 2003 (Adenocarcinoma...) : Caffeine, a nonspecific inhibitor of ATR , enhanced the cytotoxic effect of cisplatin, modestly decreased the p53 and p21WAF-1 response to cisplatin, and affected the cdc2-p34/cyclin B1 complex by decreasing both cyclin B1 protein accumulation and cdc2-p34 tyrosine 15 phosphorylation