Gene interactions and pathways from curated databases and text-mining

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CHI3L1 — MMP9

Text-mined interactions from Literome

Schmidt-Rohlfing et al., Scand J Rheumatol 2002 : The measured biochemical markers included MMP-1, MMP-3 , and MMP-13, the tissue inhibitor of MMPs ( TIMP-1 ), COMP, YKL-40 , and tenascin
Ling et al., Biochem J 2004 (Inflammation) : HC-gp39 suppressed the cytokine induced secretion of MMP1, MMP3 and MMP13, as well as secretion of the chemokine IL-8
Libreros et al., Int J Cancer 2012 (Disease Progression...) : We found that in vitro inhibition of CHI3L1 by siRNA suppressed the production of CCL2, CXCL2 and MMP-9 by macrophages