Gene interactions and pathways from curated databases and text-mining

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COL1A1 — MMP9

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Dong et al., Int J Cancer 2001 (Bone Neoplasms...) : Collagen I is a potent inducer of pro-MMP-9 in PC cells
Poitevin et al., Journal of thrombosis and haemostasis : JTH 2008 : Type I collagen induced TF expression and increased MMP-9 production
Zhang et al., Bone 2009 (Weight Gain) : Ovariectomy promoted the mRNA expression of alpha-1 type I collagen (COL) , osteoprotegerin (OPG) and receptor activator of nuclear factor-kappa B ligand ( RANKL ) ; and inhibited the mRNA expression of cathepsin K and matrix metalloproteinase-9 (MMP-9) in the proximal tibia of aged rats