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BDNF — MMP2
Text-mined interactions from Literome
Sartor et al., Clin Exp Metastasis 2002
(Brain Neoplasms...) :
At the membrane level, gelatinase MMP-2 -- mainly the activated form -- was restrained by CNTF and
BDNF to a residual 34 % with both factors ; membrane-type 1
MMP was
down-regulated to 50 % ( 10 h ) and 34 % ( 24 h ) with both factors ; and urokinase-type plasminogen activator was restrained mainly by BDNF to 70 %
Sun et al., Chin Med J (Engl) 2006
:
The stimulation of serum starved HUVECs with
BDNF caused obvious increase in MMP-2 and MMP-9 mRNA expression and
induced the
pro-MMP-2 and pro-MMP-9 activation without significant differences in proliferation
Dagnell et al., Translational research : the journal of laboratory and clinical medicine 2007
:
Therefore, we studied the
effect of NGF,
BDNF , and NT-3 on human bronchial smooth muscle cell ( HBSMC ) migration and
MMP-2 and MMP-9 secretion ...
BDNF , NT-3, and NGF
increased MMP-9, but not
MMP-2 , secretion as shown by zymography
Odate et al., Lung Cancer 2013
(Carcinoma, Large Cell...) :
In vitro assay, exogenous BDNF addition enhanced the invasion into matrigels of LCNEC cells, whereas inhibition of TrkB or
BDNF suppressed
matrix metalloproteinase-2 and -9 activities and the invasiveness