◀ Back to TP53

HDAC6 — TP53

Text-mined interactions from Literome

Wilkinson et al., Mol Cell Biol 2005 : p53 promotes SnoN and histone deacetylase interaction at an overlapping Smad binding, p53 regulatory element ( SBE/p53RE ) in AFP
Blagosklonny et al., Cancer Res 2005 : We suggest that, by either restoring or mimicking p53 trans-functions, histone deacetylase inhibitors initiate degradation of mutant p53
Chang et al., J Virol 2008 : Critical role of p53 in histone deacetylase inhibitor induced Epstein-Barr virus Zta expression
Chen et al., EMBO J 2010 : MDM2 also inhibits p53 transcriptional activity by recruiting histone deacetylase and corepressors to p53
Ozaki et al., Cell death & disease 2013 : Of note, HDAC6-specific chemical inhibitor tubacin treatment enhanced ADR mediated upregulation of p53-target gene expression, indicating that deacetylase activity of HDAC6 is required for RUNX2 mediated downregulation of p53-target gene