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NTS — SST
Text-mined interactions from Literome
Hammer et al., Life Sci 1991
:
These results suggested that
somatostatin-like immunoreactivity, released into the portal circulation, was
necessary for exogenous
neurotensin to inhibit pentagastrin stimulated gastric acid secretion under these conditions in anesthetized rats
Robbins et al., Brain Res 1985
:
The
effects of
neurotensin , vasoactive intestinal polypeptide and other neuropeptides on the secretion of
somatostatin from cerebral cortical cells
Roca et al., Regul Pept 1986
:
Vasoactive intestinal peptide,
neurotensin , substance P, Leu-enkephalin and vasopressin
had practically no effect on
somatostatin binding
Dolais-Kitabgi et al., Endocrinology 1979
:
Effect of
neurotensin on insulin, glucagon, and
somatostatin release from isolated pancreatic islets ... The
effects of
neurotensin on the release of insulin, glucagon, and
somatostatin were investigated in isolated pancreatic islets prepared from 3- to 4-day-old rats and maintained in culture for 48 h before use ... In 20-min incubations at 3 mM glucose,
neurotensin ( 10-100 nM )
increased the release of insulin, glucagon, and
somatostatin by 60 %, 90 %, and 110 %, respectively ... It is concluded that neurotensin exerts a dual effect on the endocrine pancreas in vitro : 1 ) at low glucose concentration and over short term ( 20 min ) incubations, the peptide stimulates insulin, glucagon, and somatostatin release ; and 2 ) under stimulated conditions ( high glucose or arginine ),
neurotensin inhibits insulin, glucagon, and
somatostatin release
Dolais-Kitabgi et al., Diabete Metab 1979
:
The
effects of
neurotensin on insulin and
somatostatin release were examined in isolated pancreatic islets prepared from 3-4 days rats, and maintained in culture for 48 h before use
Saito et al., Endocrinology 1980
:
Effects of substance P and
neurotensin on
somatostatin levels in rat portal plasma
Bryant et al., Gastroenterology 1982
:
Gastrin, secretin, motilin, gastric inhibitory peptide, vasoactive intestinal peptide, enteroglucagon, and
somatostatin were first
detected as early as 8 wk of age, while
neurotensin was only demonstrated at 12 wk. Adult patterns of distribution were established by 20 wk of age
Sakamoto et al., Regul Pept 1995
:
An
effect of
somatostatin on
neurotensin secretion
Rage et al., Endocrinology 1999
:
The increased levels of
somatostatin ( peptide and mRNA )
induced by
NTs were not blocked by tetrodotoxin or by glutamate receptor antagonists, suggesting that endogenous neurotransmitters ( e.g. glutamate ) were not involved in these effects