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CXCL10 — EPHB2

Text-mined interactions from Literome

Xia et al., J Neuroimmunol 2000 (Alzheimer Disease...) : Expression of the chemokine receptor CXCR3 on neurons and the elevated expression of its ligand IP-10 in reactive astrocytes : in vitro ERK1/2 activation and role in Alzheimer 's disease
Tibbles et al., J Virol 2002 (Adenovirus Infections, Human...) : Activation of p38 and ERK signaling during adenovirus vector cell entry lead to expression of the C-X-C chemokine IP-10 ... In vivo, direct inhibition of ERK and p38 signaling pathways inhibited adenovirus vector induced IP-10 expression in mouse liver 1 h following transduction
Wang et al., Biochemistry 2002 : Moreover, CXCL1 activation of PAK1 is independent of ERK1/2 activation, a conclusion based on the observations that the inhibition of MEK-ERK activation by expression of dominant negative ERK or by the MEK inhibitor, PD98059, has no effect on CXCL1 induced PAK1 activation or CXCL1 induced chemotaxis
Wang et al., Biochemistry 2003 : Moreover, CXCL10 can inhibit CXCL1 induced PAK1 and ERK activation as well as the CXCL1 induced chemotaxis through decreasing CXCL1 binding to cell surface heparan sulfate
Ottaiano et al., Cancer Immunol Immunother 2005 (Carcinoma...) : Further, CXCL12 activated ERK1/2 in SW480 cells
Goldberg-Bittman et al., Cytokine 2005 (Neuroblastoma) : Further detailed analysis was performed on the NUB6 and SK-NMC neuroblastoma cells, showing that CXCL10 induced potent Erk phosphorylation in a G ( alpha ) i-dependent manner
Granata et al., Eur J Immunol 2006 : sPLA ( 2 ) induced the phosphorylation of the MAPK p38 and ERK1/2 , and inhibition of these kinases by SB203580 and PD98059, respectively, reduced TNF-alpha and CXCL8 release
Sai et al., J Biol Chem 2006 : Although both mutant and wild-type receptors could mediate Akt and Erk activation in response to CXCL8 , the level of activation of these two kinases was much lower in the cell line expressing the mutant receptors
Hung et al., Pediatr Allergy Immunol 2007 : The suppressive effect on MDC and IP-10 may, at least in part, involve the down-regulation of LPS induced p38 and ERK-MAPK expression
Petrai et al., Int J Biochem Cell Biol 2008 : In cells expressing CXCR3-A, CXCL10 ( IP-10 ) at nanomolar concentrations induced activation of ERK , Akt, and Src, as previously described in human vascular pericytes ... In cells expressing CXCR3-A, CXCL10 ( IP-10 ) at nanomolar concentrations induced activation of ERK , Akt, and Src, as previously described in human vascular pericytes
Qi et al., J Cell Physiol 2009 : JAKs inhibitors suppressed IFN-gamma plus TNF-alpha induced production of CXCL10 in parallel with activation of STAT1 and NF-kappaB, while ERK inhibitor suppressed production of CXCL10 as well as activation of NF-kappaB, but not that of STAT1
Sambandam et al., Oncogene 2013 (Carcinoma, Squamous Cell...) : Also, CXCL13 significantly increased p-ERK1/2 in SAKA-T and MC3T3-E1 cells
Rigo et al., PloS one 2012 : In contrast, the structural variant [ N33A ] CXCL12 triggered no ß-arrestin dependent phosphorylation of ERK1/2 , and signaled via G protein dependent pathways alone ... We conclude that both recombinant CXCL12 and its structural variant [ N33A ] CXCL12 may transinhibit HER1 via G-proteins/calmodulin/calcineurin, but [ N33A ] CXCL12 does not activate ß-arrestin dependent ERK1/2 phosphorylation and retains a stronger inhibitory effect
Nawaz et al., Exp Eye Res 2013 (Diabetic Retinopathy...) : On the other hand, phosphorylation of ERK induced by VEGF and MCP-1 was inhibited by PF-4, Mig and IP-10