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FGF19 — FGF4

Pathways - manually collected, often from reviews:

• Reactome Reaction: FGF4 → FGF19 (reaction) Carpenter et al., Exp Cell Res 1999, Hart et al., Mol Biol Cell 2001, Wong et al., Proc Natl Acad Sci U S A 2002, Lax et al., Mol Cell 2002, Fong et al., J Biol Chem 2003, Mohammadi et al., Nature 1992, Agazie et al., Oncogene 2003, Mohammadi et al., Mol Cell Biol 1991, Ahmed et al., Biochem J 2008, Schüller et al., Biochem J 2008, Klint et al., J Biol Chem 1995, Wang et al., Mol Cell Biol 1994, Mohammadi et al., Mol Cell Biol 1996, Ong et al., Biochem Biophys Res Commun 1996, Kanai et al., J Biol Chem 1997, Kouhara et al., Cell 1997, Ong et al., Biochem Biophys Res Commun 1997, Hadari et al., Mol Cell Biol 1998

Text-mined interactions from Literome

Kurosu et al., J Biol Chem 2007 : Accordingly, FGF19 , but not FGF21, activates FGF signaling in hepatocytes that primarily express FGFR4 and reduces transcription of CYP7A1 that encodes the rate limiting enzyme for bile acid synthesis
Blagovic et al., PloS one 2011 : Then we induce FGF4 signaling in minimal chemically defined medium ( N2B27 ) and inhibit FGF signaling in fully supplemented differentiation medium with cell secreted factors to determine that the non-FGF cell secreted factors are required to promote growth of differentiating mESCs