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EPHB2 — ERBB2

Text-mined interactions from Literome

Spencer et al., J Cell Biol 2000 (Adenocarcinoma...) : Overexpression of ErbB2 in cells devoid of other ErbB receptor members is sufficient to promote ERK activation and CAS/Crk coupling, leading to cell migration
Xia et al., Oncogene 2004 (Breast Neoplasms) : Inhibition of p95ErbB2 , p185ErbB2, and EGFR phosphorylation by GW572016 resulted in the inhibition of downstream phospho-Erk1/2 , phospho-AKT, and cyclin D steady-state protein levels
Gunawardane et al., Cancer Res 2005 (Breast Neoplasms...) : Constitutive activation of the extracellular signal regulated kinase ( ERK ) pathway also enhanced PDEF induced motility and invasion, suggesting that activation of the ERK/mitogen activated protein kinase by ErbB2 and CSF-1R/CSF-1 can cooperate with PDEF to promote motility and invasion
Choi et al., Cancer Lett 2006 (Breast Neoplasms) : Blocking the ERK , p38 kinase or PI3-kinase activity had no effect on the resveratrol-inducible transactivation of the erbB2 gene and the ErbB2 expression level
Borges et al., Cell Signal 2007 : In breast cancer cells overexpressing ErbB2, Erk5 dual phosphorylation required ErbB2 tyrosine kinase activity ; however, Erk5 nuclear residency did not require ErbB2 activity
Scheving et al., Am J Physiol Gastrointest Liver Physiol 2008 : Cultured rat hepatocytes upregulate Akt and ERK in an ErbB-2 dependent manner
Mehta et al., Biomaterials 2010 : Phenotypic differences between soluble and tethered EGF stimulation of cells on peptide gels are correlated with differences in expression and phosphorylation the EGF receptor and its heterodimerization partner ErbB2 , and activation of the downstream signaling node ERK1/2
Chia et al., Neoplasia (New York, N.Y.) 2011 (Breast Neoplasms) : Furthermore, we show that AR-mediated induction of ERK requires ErbB2 , and AR activity, in turn, regulates ErbB2 expression as an AR target gene
Berger et al., J Immunother 2011 (Neoplasms, Glandular and Epithelial) : We have in the current study compared the effects of Nimotuzumab and Cetuximab on binding of EGF as well as on inhibition of constitutive EGFR-ErbB2 dimerization and downstream activation of Erk
Grassian et al., Genes Dev 2011 : Overexpression of ErbB2 maintains PDH flux by suppressing PDK4 expression in an Erk dependent manner, and Erk signaling also regulates PDH flux in ECM attached cells
Zhou et al., Zhonghua Yi Xue Za Zhi 2012 (MAP Kinase Signaling System) : After a pretreatment of antibodies of ErbB2 , ErbB3, inhibitors of p38MAPK, ERK1/2 , MSK1 and antibody of CREB and a stimulation of NRG-1ß, the expression of MUC5AC decreased ( 0.221 ± 0.033, 0.238 ± 0.044, 0.386 ± 0.021, 0.352 ± 0.022, 0.294 ± 0.017, 0.252 ± 0.019 ) versus the NRG-1ß group ( 0.650 ± 0.134 )