◀ Back to IL13
IL13 — IL2RA
Text-mined interactions from Literome
Smith et al., Allergy 2004
(Asthma) :
CD4 ( + )
CD25 ( + ) T cells
suppressed both proliferation and
IL-13 production by CD4 ( + ) CD25 ( - ) T cells before and after therapy but peptide therapy was not associated with any change in suppressive activity of these cells
Benghiat et al., Transplantation 2005
:
Finally, natural
CD25 ( + ) Treg cells
inhibited the production of interleukin (IL)-2, interferon-gamma, IL-5, and
IL-13 in mixed lymphocyte culture in a dose dependent manner
Leech et al., J Immunol 2007
(Asthma...) :
Most convincingly, transfer of CD4 ( + )
CD25 ( + ) Foxp3 ( + ) T cells from Ag naive mice ( natural Tregs ) abolished AAI, decreased dMLN IL-5 and IL-13 secretion, increased dMLN IL-10 secretion, abolished IgE, and decreased IgG1 Abs. Blocking IL-10 receptor function in vivo did not block the anti-inflammatory function of transferred natural Tregs but did
restore dMLN IL-5 and
IL-13 secretion
Zhao et al., Leukemia 2008
(Hypersensitivity, Delayed) :
sorafenib also caused G ( 0 ) /G ( 1 ) phase arrest,
inhibition of
CD25 and CD69 expression,
interleukin-2 production and LCK phosphorylation in the T cells ; all of these effects exhibited dose and time dependence
Chaput et al., Gut 2009
(Adenocarcinoma...) :
Finally,
interleukin 6 and TGF beta 1 synergistically
induced the generation of CD8 ( + )
CD25 ( + ) Foxp3 ( + ) T cells ex vivo
Shirakawa et al., Mol Cell Biol 1989
:
Identical results were obtained with the human natural killer-like cell line YT, which can be induced to express the
interleukin-2 receptor alpha subunit in
response to
interleukin-1 , cyclic AMP, or phorbol 12-myristate 13-acetate
Burlinson et al., Immunol Lett 1995
:
IL-4 is the only cytokine apparently capable of promoting CD25 expression in human high-density quiescent tonsillar B cells ; neither IL-10 nor
IL-13 could
induce CD25 expression