Gene interactions and pathways from curated databases and text-mining

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CSF2 — IFI44

Text-mined interactions from Literome

Hallsworth et al., Am J Respir Crit Care Med 2001 (Asthma...) : GM-CSF release is p42/p44 ERK dependent and is tonically suppressed by a mechanism that is partially dependent on p38 MAP kinase, though direct inhibition of cyclooxygenase (COX) activity due to poor inhibitor selectivity may also contribute
Dauffy et al., J Leukoc Biol 2006 : Here, we show that Ifi204 was transcriptionally activated in response to M-CSF , and FD-Fms cells decreased their growth and committed toward a macrophage morphology ; this induction was abrogated when the differentiation signal of the M-CSF receptor was blocked ; the Ifi204 gene was also induced during macrophage differentiation controlled by leukemia inhibitory factor ; and the Ifi204 gene is expressed in different mature monocyte/macrophage cells
Dohgu et al., Journal of neuroinflammation 2011 : These results show that p44/42 and p38 MAPK signaling pathways mediate the LPS enhanced release of IL-6 and GM-CSF