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EPHB2 — KLF4

Text-mined interactions from Literome

Zheng et al., J Biol Chem 2009 : We demonstrated that Klf4 directly binds to the 5 ' regulatory region of RAR alpha, down-regulates RAR alpha expression, and specifically inhibits RAR alpha mediated phosphatidylinositol 3-kinase (PI3K) and ERK signaling in cultured VSMCs induced by the synthetic retinoid Am80
Clark et al., Microcirculation 2011 : MEK5 is activated by shear stress, activates ERK5 and induces KLF4 to modulate TNF responses in human dermal microvascular endothelial cells ... LSS activates ERK5 and induces KLF4 in cultured HDMECs ... MEK5 induction of KLF4 is mediated by ERK5 ... MEK5 activation by LSS inhibits inflammatory responses in microvascular ECs, in part through ERK5 dependent induction of KLF4
Sunadome et al., Dev Cell 2011 : Remarkably, Klf2 and Klf4 expression are also upregulated during differentiation in an ERK5 dependent manner, and knockdown of Klf2 or Klf4 specifically suppresses muscle cell fusion