◀ Back to MDM2

ESR1 — MDM2

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Bind_translation Interaction: ESR1 — MDM2 (affinity chromatography technology) Liu et al., Cancer Res 2000*
• IRef Biogrid Interaction: ESR1 — MDM2 (direct interaction, pull down) Saji et al., Biochem Biophys Res Commun 2001*
• IRef Biogrid Interaction: ESR1 — MDM2 (direct interaction, pull down) Liu et al., Cancer Res 2000*
• IRef Biogrid Interaction: ESR1 — MDM2 (physical association, affinity chromatography technology) Kinyamu et al., Mol Cell Biol 2003*
• IRef Biogrid Interaction: ESR1 — MDM2 (direct interaction, pull down) Duong et al., Cancer Res 2007*
• IRef Biogrid Interaction: ESR1 — MDM2 (physical association, affinity chromatography technology) Duong et al., Cancer Res 2007*
• IRef Biogrid Interaction: ESR1 — MDM2 (direct interaction, two hybrid) Saji et al., Biochem Biophys Res Commun 2001*
• MIPS CORUM Er-alpha-p53-hdm2 complex: Er-alpha-p53-hdm2 complex complex (ESR1-MDM2-TP53) Liu et al., Cancer Res 2000*
• IRef Corum Interaction: Complex of ESR1-MDM2-TP53 (association, pull down) Liu et al., Cancer Res 2000*
• IRef Hprd Interaction: ESR1 — MDM2 (in vitro) Liu et al., Cancer Res 2000*, Saji et al., Biochem Biophys Res Commun 2001*
• IRef Intact Interaction: MDM2 — ESR1 (physical association, two hybrid) Saji et al., Biochem Biophys Res Commun 2001*
• IRef Intact Interaction: MDM2 — ESR1 (physical association, pull down) Saji et al., Biochem Biophys Res Commun 2001*
• IRef Ophid Interaction: MDM2 — ESR1 (aggregation, interologs mapping) Brown et al., Bioinformatics 2005
• IRef Ophid Interaction: MDM2 — ESR1 (aggregation, confirmational text mining) Liu et al., Cancer Res 2000*

Text-mined interactions from Literome

Kato et al., J Biol Chem 2002 (Cell Transformation, Neoplastic) : In addition, overexpression of wild type ERalpha in NIH3T3 cells resulted in the significant increase in the MDM2 protein level and the resultant suppression of p53 transcriptional activity
Seifert et al., Int J Oncol 2009 (Breast Neoplasms) : This increase resulted in transactivation of ERalpha and induction of ERalpha mediated transcription of Hdm2 and SOCS3
Kim et al., J Mol Endocrinol 2011 (Breast Neoplasms) : MDM2 regulates estrogen receptor a and estrogen responsiveness in breast cancer cells
Sanchez et al., Oncogene 2013 : Coordinate regulation of estrogen receptor ß degradation by Mdm2 and CREB binding protein in response to growth signals