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NFKBIA — RELB

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Bind Interaction: Complex of 16 proteins Bouwmeester et al., Nat Cell Biol 2004
• IRef Bind Interaction: Complex of 11 proteins Bouwmeester et al., Nat Cell Biol 2004
• IRef Bind Interaction: Complex of RELB-REL-TNIP2-NFKB1-RELA-NFKBIA-NFKB2-IKBKG-NFKB1 Bouwmeester et al., Nat Cell Biol 2004
• IRef Biogrid Interaction: NFKBIA — RELB (physical association, affinity chromatography technology) Robert et al., Oncogene 2009*
• MIPS CORUM TNF-alpha/NF-kappa B signaling complex (CHUK, KPNA3, NFKB2, NFKBIB, REL, IKBKG, NFKB1, NFKBIE, RELB, NFKBIA, RELA, TNIP2): TNF-alpha/NF-kappa B signaling complex (CHUK, KPNA3, NFKB2, NFKBIB, REL, IKBKG, NFKB1, NFKBIE, RELB, NFKBIA, RELA, TNIP2) complex (CHUK-IKBKG-KPNA3-NFKB1-NFKB2-NFKBIA-NFKBIB-NFKBIE-REL-RELA-RELB-TNIP2) Bouwmeester et al., Nat Cell Biol 2004
• MIPS CORUM TNF-alpha/Nf-kappa B signaling complex (RPL6, RPL30, RPS13, CHUK, DDX3X, NFKB2, NFKBIB, REL, IKBKG, NFKB1, MAP3K8, RELB, GLG1, NFKBIA, RELA, TNIP2, GTF2I): TNF-alpha/Nf-kappa B signaling complex (RPL6, RPL30, RPS13, CHUK, DDX3X, NFKB2, NFKBIB, REL, IKBKG, NFKB1, MAP3K8, RELB, GLG1, NFKBIA, RELA, TNIP2, GTF2I) complex (CHUK-DDX3X-GLG1-GTF2I-IKBKG-MAP3K8-NFKB1-NFKB2-NFKBIA-NFKBIB-REL-RELA-RELB-RPL30-RPL6-RPS13-TNIP2) Bouwmeester et al., Nat Cell Biol 2004
• IRef Corum Interaction: Complex of 18 proteins (association, tandem affinity purification) Bouwmeester et al., Nat Cell Biol 2004
• IRef Corum Interaction: Complex of 13 proteins (association, tandem affinity purification) Bouwmeester et al., Nat Cell Biol 2004
• IRef Hprd Interaction: Complex of 290 proteins (in vivo) Bouwmeester et al., Nat Cell Biol 2004
• IRef Hprd Interaction: Complex of 145 proteins (in vivo) Bouwmeester et al., Nat Cell Biol 2004
• IRef Intact Interaction: NFKBIA — RELB (physical association, tandem affinity purification) Bouwmeester et al., Nat Cell Biol 2004
• IRef Ophid Interaction: NFKBIA — RELB (aggregation, interologs mapping) Brown et al., Bioinformatics 2005

Text-mined interactions from Literome

Shain et al., J Cell Biochem 1999 : RelB activation in SR1 cells did not require an increase in RelB expression or result from a decrease in the levels of IkappaB alpha or p105, proteins previously shown to bind to and inhibit the activity of the Rel proteins
Chen et al., Clinical and vaccine immunology : CVI 2009 : In contrast, we report herein that RelB is required for sustained expression of anti-inflammatory IkappaBalpha in LPS-tolerant THP-1 cells ... RelB transcription activation requires binding to the IkappaBalpha proximal promoter along with NF-kappaB p50 and is associated with an apparent dimer exchange with p65
Weih et al., Oncogene 1996 : Overexpression of RelB in transgenic mice does not affect I kappa B alpha levels : differential regulation of RelA and RelB by the inhibitor protein ... Interestingly, I kappa B alpha protein levels are not altered in the RelB-transgenic animals, indicating that within the same cell type RelA and RelB complexes are differentially regulated by I kappa B alpha
Ferreira et al., J Biol Chem 1998 : Wild type IkappaBalpha expression was concomitant with RelB up-regulation, suggesting that RelB could be involved in transcription of IkappaBalpha through binding to an alternative site