Gene interactions and pathways from curated databases and text-mining

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IGFBP1 — NOS2

Text-mined interactions from Literome

Beltrame et al., Placenta 2013 : Both cyclooxygenase-2 and inducible NOS mediated LPA effect on IGFBP-1 and IL-10 expression
Dong et al., J Leukoc Biol 1995 : Taken together, these data indicate that PP1/2A activities are involved in the regulation of iNOS gene expression in murine macrophages
Pahan et al., J Biol Chem 1998 : This study suggests that the stimulation of iNOS expression in astrocytes by inhibitors of PP 1/2A is possibly due to the stimulation of NF-kappaB activation ; however, activation of NF-kappaB is not sufficient for the induction of iNOS in macrophages and that apart from NF-kappaB some other signaling pathway ( s ) sensitive to PP 1 and/or PP 2A is/are possibly involved in the regulation of iNOS in macrophages