Gene interactions and pathways from curated databases and text-mining

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CSE — EPHB2

Text-mined interactions from Literome

Kim et al., Exp Mol Med 2009 : In isolated rat AMs, CSE induced MMP-9 expression and phosphorylation of ERK and Akt ... A chemical inhibitor of MEK1/2 or PI3K reduced phosphorylation of ERK or Akt, respectively, and also inhibited CSE mediated MMP-9 induction ... Simvastatin attenuated CSE mediated activation of RAS and phosphorylation of ERK , Akt, p65, IkappaB, and nuclear AP-1 or NF-kappaB activity
Shen et al., Am J Pathol 2011 (Pulmonary Disease, Chronic Obstructive) : Further examination showed that EGR-1 in turn regulated Erk1/2 activity because inhibition of EGR-1 transcription activity decreased CSE induced Erk1/2 phosphorylation
Simone et al., PloS one 2011 : Lycopene further inhibited CSE induced phosphorylation of the redox-sensitive ERK1/2 , JNK and p38 MAPKs
Palozza et al., Inflamm Allergy Drug Targets 2012 : Moreover, lycopene inhibited CSE induced ERK1/2 and NF-?B activation in a dose dependent manner