Gene interactions and pathways from curated databases and text-mining

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HGF — NOS2

Text-mined interactions from Literome

Purdie et al., Cardiovasc Res 2002 : HGF induced iNOS expression was partially abrogated in the presence of the phosphatidylinositol 3-kinase ( PI 3-kinase ) inhibitor LY294002, but not the Src kinase inhibitor, PP1
Sun et al., J Neurosci 2002 (Amyotrophic Lateral Sclerosis...) : HGF prevented induction of caspase-1 and inducible nitric oxide synthase (iNOS) in motoneurons and retained the levels of the glial-specific glutamate transporter ( excitatory amino acid transporter 2/glutamate transporter 1 ) in reactive astrocytes
Tse et al., Placenta 2002 : TGF-beta1 was found to significantly decrease HGF induced iNOS expression therefore suggesting a novel mechanism by which TGF-beta1 could regulate motility and invasion
Makondo et al., Biochem J 2003 : Hepatocyte growth factor activates endothelial nitric oxide synthase by Ca ( 2+ ) - and phosphoinositide 3-kinase/Akt dependent phosphorylation in aortic endothelial cells
Lu et al., Environ Toxicol Pharmacol 2012 (Drug-Induced Liver Injury) : The expressions of ICAM-1, vimentin, prohibitin, HGF , c-MET and GSTA1 were also regulated by dioscin and iNOS was also involved in the effects of this agent