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CDC20 — CDH1
Pathways - manually collected, often from reviews:
-
WikiPathways Cell Cycle:
CDC20/APC
→
CDH1/APC
(activation)
Text-mined interactions from Literome
Kramer et al., Mol Biol Cell 2000
:
The ordered
activation of the ubiquitin protein ligase anaphase promoting complex (APC) or cyclosome by
CDC20 in metaphase and by
CDH1 in telophase is essential for anaphase and for exit from mitosis, respectively
Wäsch et al., Nature 2002
:
Furthermore, Clb5 degradation was thought to be necessary for effective dephosphorylation and
activation of the APC regulatory subunit
Cdh1 ( also known as Hct1 ) and the cyclin dependent kinase inhibitor Sic1 by the phosphatase
Cdc14 , allowing mitotic kinase inactivation and mitotic exit