◀ Back to IL7
IL15 — IL7
Text-mined interactions from Literome
Ogata et al., J Immunol 1999
:
Although IL-15 is known as a potent stimulator of TNF-alpha, its activity was not abolished by addition of anti-TNF-alpha Ab. Interestingly, IL-2 and
IL-7 , which utilize some IL-15R components, had no effect on osteoclast differentiation, but pretreatment with IL-2 or IL-7 of bone marrow cells before the addition of IL-15
inhibited the enhancing activity of
IL-15
D'Agostino et al., Scand J Immunol 2004
(Leishmaniasis, Visceral) :
Interleukin-15 , as interferon-gamma,
induces the killing of Leishmania infantum in phorbol-myristate-acetate activated macrophages increasing
interleukin-12
Surh et al., Semin Immunol 2005
:
In essence, homeostasis of naïve T cells is regulated by
IL-7 and self-MHC/peptide ligands and homeostasis of memory CD8 cells is
controlled by IL-7 and
IL-15
Liu et al., J Immunother 2006
:
IL-7 alone did not
induce significant proliferation of any tumor-reactive T-cell population, whereas IL-2 and
IL-15 induced significant proliferation of tumor-reactive T lymphocytes from both sources
Quinci et al., Eur J Immunol 2012
:
IL-15 inhibits
IL-7Ra expression by memory-phenotype CD8? T cells in the bone marrow