Gene interactions and pathways from curated databases and text-mining

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ABCA1 — PI3

Text-mined interactions from Literome

Huwait et al., Cell Signal 2011 : The expression of ApoE and ABCA1 induced by synthetic or natural LXR ligands [ TO901317, GW3965, and 22- ( R ) -hydroxycholesterol ( 22- ( R ) -HC ), respectively ] was attenuated by inhibitors of c-Jun N-terminal kinase (JNK) ( curcumin and SP600125 ) and phosphoinositide 3-kinase (PI3K) ( LY294002 )
Liu et al., Biochim Biophys Acta 2012 (Diabetes Mellitus, Type 2...) : Silencing ABCA1 in McArdle rat hepatoma cells results in diminished assembly of large ( > 10nm ) nascent HDL particles, diminished PI3 kinase activation, and increased secretion of large, TG-enriched VLDL1 particles