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EGR1 — LEP

Text-mined interactions from Literome

Zhou et al., Life Sci 2009 : The effects of leptin on the expression and trans-activation activity of early growth response-1 (Egr-1) are examined by using real-time PCR, Western blotting analysis, transient transfection, and electrophoretic mobility shift assay ... Moreover, leptin induces the expression and activity of Egr-1 through activation of extracellular signal regulated kinase ( ERK ) or phosphatidylinositol 3-kinase/AKT signaling ( PI-3K/AKT ) pathway
Rucinski et al., Int J Mol Med 2010 : Expression of only two studied genes, GPR39v1 and EGR1 , was regulated by OBS
de Lartigue et al., Endocrinology 2010 : EGR1 Is a target for cooperative interactions between cholecystokinin and leptin , and inhibition by ghrelin, in vagal afferent neurons ... Leptin stimulates EGR1 expression ; leptin alone does not stimulate nuclear translocation, but it strongly potentiates the action of CCK ... Ghrelin inhibits CCK stimulated nuclear translocation of EGR1 and leptin stimulated EGR1 expression