Edgtton et al., J Am Soc Nephrol 2008
:
Blocking both CD86 and CD80 profoundly inhibited CD4 ( + ) cell proliferation, but CD86 was the dominant CD28 ligand in the early proliferative response of CD4 ( + ) cells
Fuse et al., Cell Immunol 2011
(Vaccinia) :
Differential requirements for CD80/86-CD28 costimulation in primary and memory CD4 T cell responses to vaccinia virus