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CD36 — FOS
Text-mined interactions from Literome
Lee et al., Life Sci 2009
:
Up-regulation of SR-A and
CD36 by resistin
resulted from activation of
AP-1 and PPARgamma, respectively, and this was confirmed by the lack of activation of either after AP-1 inhibition using curcumin or SP600125, or PPARgamma inhibition using GW9662, respectively
Li et al., Int J Mol Med 2013
:
The reduced
CD36 expression following kaempferol treatment
involved the inhibition of
c-Jun-activator protein-1 (AP-1) nuclear translocation ... The inhibition of AP-1 using the inhibitor, SP600125, confirmed this involvement, as the
AP-1 inhibition significantly
augmented the kaempferol induced reduction in
CD36 expression ... In conclusion, the
c-Jun-AP-1 dependent downregulation of
CD36 and the HO-1 dependent upregulation of ABCG1, SR-BI and ABCA1 may mediate the beneficial effects of kaempferol on foam cell formation