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AQP3 — EGFR

Text-mined interactions from Literome

Herrlich et al., Proc Natl Acad Sci U S A 2004 (MAP Kinase Signaling System) : Role of proneuregulin 1 cleavage and human epidermal growth factor receptor activation in hypertonic aquaporin induction
Cao et al., Biochem J 2006 : EGFR mediated expression of aquaporin-3 is involved in human skin fibroblast migration ... Furthermore, an EGFR ( EGF receptor ) kinase inhibitor, PD153035, blocked EGF induced AQP3 expression and cell migration
Ji et al., Cancer Chemother Pharmacol 2008 (Ovarian Neoplasms) : We also find that curcumin, a well known anti-ovarian cancer drug, down-regulates AQP3 expression and reduces cell migration in CaOV3, and the effects of curcumin are mediated , at least in part, by its inhibitory effects on EGFR and downstream AKT/ERK activation
Song et al., Int J Mol Med 2008 (MAP Kinase Signaling System) : PD153035, an EGFR inhibitor, and U0126, an ERK inhibitor, inhibit atRA induced upregulation of AQP3 ... Collectively, our results indicate that the effect of atRA on AQP3 expression is at least partly mediated by EGFR/ERK signaling in cultured human skin keratinocytes