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AKT2 — HK3
Text-mined interactions from Literome
Gottlob et al., Genes Dev 2001
:
First,
Akt increases mitochondria associated
hexokinase activity
Wang et al., Neurosci Lett 2008
:
The hypothesis that neurotrophic factor dependent activation of Akt would regulate hexokinase association with the mitochondria was tested and quantitative Western blotting showed no effect of blockade of the phosphoinositide 3-kinase ( PI 3-kinase ) /Akt pathway using the inhibitor LY294002, indicating this interaction of
hexokinase with mitochondria was not neurotrophic factor or
Akt dependent