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AKT2 — PLXNB1
Text-mined interactions from Literome
Gómez Román et al., Translational research : the journal of laboratory and clinical medicine 2008
(Carcinoma, Renal Cell...) :
Plexin B1 has been implicated in the
regulation of
Akt , which is an activated pathway in renal cell neoplasms, and only 1 report has emphasized its role as an oncogenic factor
Stevens et al., J Invest Dermatol 2010
(Melanoma...) :
Plexin B1 also
activated Akt in melanoma ... However, because
plexin B1 activates
Akt , a multifunctional protein involved in tumor progression in several cancers, plexin B1 may function as a tumor promoter in melanomas not driven by c-Met activation
Kato et al., Cancer Sci 2011
(Carcinoma, Pancreatic Ductal...) :
The binding of Sema4D to
plexinB1 induced small GTPase Ras homolog gene family, member A activation and
resulted in the phosphorylation of MAPK and
Akt