Gene interactions and pathways from curated databases and text-mining

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AKT2 — PLXNB1

Text-mined interactions from Literome

Gómez Román et al., Translational research : the journal of laboratory and clinical medicine 2008 (Carcinoma, Renal Cell...) : Plexin B1 has been implicated in the regulation of Akt , which is an activated pathway in renal cell neoplasms, and only 1 report has emphasized its role as an oncogenic factor
Stevens et al., J Invest Dermatol 2010 (Melanoma...) : Plexin B1 also activated Akt in melanoma ... However, because plexin B1 activates Akt , a multifunctional protein involved in tumor progression in several cancers, plexin B1 may function as a tumor promoter in melanomas not driven by c-Met activation
Kato et al., Cancer Sci 2011 (Carcinoma, Pancreatic Ductal...) : The binding of Sema4D to plexinB1 induced small GTPase Ras homolog gene family, member A activation and resulted in the phosphorylation of MAPK and Akt