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PEBP1 — RELA

Text-mined interactions from Literome

Yeung et al., Mol Cell Biol 2001 : Raf kinase inhibitor protein interacts with NF-kappaB inducing kinase and TAK1 and inhibits NF-kappaB activation ... Modulation of RKIP expression levels affected NF-kappaB signaling independent of the MAPK pathway
Theroux et al., Brain Res Bull 2007 (Olfaction Disorders) : Raf kinase inhibitory protein ( RKIP-1 ) is involved in the regulation of the MAP kinase, NF-kappaB , and GPCR signaling pathways
Zeng et al., Expert Opin Ther Targets 2008 (Cell Transformation, Neoplastic...) : In mammals, RKIP regulates activation of MAPK, NF-kappaB and G protein coupled receptors ( GPCRs )
Baritaki et al., Cancer Res 2009 (Adenocarcinoma...) : We show that NPI-0052 inhibits both NF-kappaB and Snail and induces RKIP expression, thus resulting in cell sensitization to CDDP and TRAIL
Tang et al., FEBS Lett 2010 (Neoplasms) : RKIP inhibits NF-kappaB in cancer cells by regulating upstream signaling components of the IkappaB kinase complex ... Since NF-kappaB target gene expression is subject to negative regulation involving the optimal induction of negative regulators, our data support a hypothesis that RKIP inhibits NF-kappaB activity via the auto-regulatory feedback loop by rapidly inducing the expression and synthesis of inhibitors of NF-kappaB activation
Baritaki et al., Crit Rev Immunol 2010 (Neoplasms...) : Because RKIP negatively regulates NF-kappaB , we propose that the resistant cell phenotype could be maintained through Snail mediated RKIP suppression which supports the constitutive NF-kappaB activation