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BCL10 — PI3

Text-mined interactions from Literome

Leverrier et al., Cell Death Differ 1999 : Role of PI3-kinase in Bcl-X induction and apoptosis inhibition mediated by IL-3 or IGF-1 in Baf-3 cells ... In this study, we have investigated the role of PI3-kinase in the regulation of Bcl-X expression and in the survival of Baf-3 cells
Liu et al., Oncogene 2000 (MAP Kinase Signaling System) : The PI-3K specific inhibitor wortmannin did not affect hGM-CSF dependent anti gamma irradiation induced apoptosis nor bcl-X ( L ) induction, thus bcl-X ( L ) but not PI-3K pathway seems to be involved in hGM-CSF dependent anti gamma irradiation induced apoptosis
Fabregat et al., Hepatology 2000 : PI 3-kinase inhibitors completely block the protective effect of EGF on TGF-beta induced bcl-x ( L ) down-regulation
Fornoni et al., Am J Pathol 2001 : The regulation of Bcl-xL by HGF was mediated by the PI3'-K but not by the MEK-1 pathway
van der Kuip et al., Blood 2001 : The fibronectin mediated antiapoptotic mechanism in Bcr-Abl-active cells was not mediated by overexpression of Bcl-XL or Bcl-2 but required an active phosphatidylinositol 3-kinase (PI-3K)
Bae et al., Cancer Res 2006 (Adenocarcinoma...) : Bcl-w overexpression also activated phosphoinositide 3-kinase (PI3K) , Akt, and Sp1, and the blocking effects of each of these components using pharmacologic inhibitors, dominant negative mutants, or small interfering RNA abolished the ability of Bcl-w to induce MMP-2 and cell invasion
Moriya et al., Hepatology 2012 (Disease Models, Animal...) : This retained expression of Bcl-xL is inhibited by the phosphatidylinositol 3-kinase (PI3K) inhibitor LY294002