Gene interactions and pathways from curated databases and text-mining

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AKT2 — PRKCZ

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Martelli et al., Leukemia 2003 : At variance with Ly294002, the Akt inhibitor did not negatively affect phosphorylation of protein kinase C-zeta and it was less effective in downregulating p70S6 kinase (p70S6K) activity
Brubaker et al., Endocrinology 2004 : The proliferative effects of GLP-1 appear to involve multiple intracellular pathways, including stimulation of Akt , activation of protein kinase Czeta , and transactivation of the epidermal growth factor receptor through the c-src kinase
Corbould et al., J Endocrinol 2007 (Insulin Resistance...) : In the glucose metabolic pathway of insulin signaling, treatment of cells with T 10 nmol/l did not alter insulin stimulated phosphorylation of insulin receptor substrate-1 or Akt , but insulin stimulated phosphorylation of protein kinase C (PKC) zeta was impaired