Gene interactions and pathways from curated databases and text-mining

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BDNF — REST

Text-mined interactions from Literome

Tabuchi et al., Biochem Biophys Res Commun 2002 : To address this, we investigated the effect of REST/NRSF and REST4 on the activity dependent activation of BDNF gene promoter I (BDNFp-I) using cultured rat cortical neurons
Abuhatzira et al., Epigenetics 2007 : The elevated levels of REST and CoREST in the brain of RTT patients and MeCP2 deficient mice result in downregulation of BDNF , apparently by their binding to the RE1 ( element ) located between the first two promoters of the BDNF gene
Hara et al., Biochem Biophys Res Commun 2009 (Calcium Signaling) : Remote control of activity dependent BDNF gene promoter-I transcription mediated by REST/NRSF
Datta et al., J Biol Chem 2011 (Huntington Disease) : Such activation of REST down-regulated expression of REST target genes, such as brain derived neurotrophic factor (BDNF) or proenkephalin (PENK)