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IL2 — SLCO6A1

Text-mined interactions from Literome

Hashimoto et al., J Clin Invest 1992 (Leukemia, T-Cell) : In the current studies, human T cell proliferation and interleukin 2 production by Jurkat cells were inhibited by GST or AUR at pharmacologically relevant concentrations
Li et al., Acta Biochim Biophys Sin (Shanghai) 2004 : The results suggested that GST-PD-1 could competently block the interaction between PD-L1 and PD-1 and increase the production of IL-2 and IFN-gamma of phytohemagglutinin activated T cells
Zhou et al., Molecules (Basel, Switzerland) 2012 (Disease Models, Animal...) : Enhanced lipid peroxidation in the gastric cancer animals was accompanied by significant decreases in the activities of GSH, GPx, GST and GR. Administration of FFKSIL significantly enhanced serum IgA, IgG, IgM, IL-2 , IL-4 and IL-10 levels, decreased serum IL-6 and TNF-a levels, lowered the levels of lipid peroxides and enhanced GSH levels and activities of GSH dependent enzymes
Hirohata et al., Clin Immunol Immunopathol 1996 (Arthritis, Rheumatoid) : Moreover, GST suppressed the expression of IL-2R ( CD25 ) and transferrin receptor ( CD71 ) on SA-stimulated B cells
Sfikakis et al., Immunopharmacol Immunotoxicol 1998 : Using mRNA dot-blot analysis and hybridization with an IL-2-specific probe we found that GST , similarly to dexamethasone that served as control, suppressed the PHA induced IL-2 mRNA accumulation dose-dependently