Gene interactions and pathways from curated databases and text-mining

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IL1RN — IL5

Text-mined interactions from Literome

Mühlberg et al., J Clin Endocrinol Metab 2000 (Graves Disease) : Recent data have indicated that orbital fibroblasts ( OF ) can be stimulated to produce marked quantities of interleukin-1 receptor antagonist ( IL-1RA ), a powerful inhibitor of the proinflammatory activities of interleukin-1 in the orbital tissues in Graves ' ophthalmopathy ( GO )
Kovár et al., Parasitol Res 2002 : ELISA ( protein level ) and RNAse protection assay ( mRNA level ) showed that SGE enhanced interleukin (IL)-1alpha, IL-1beta, IL-1Ra , IL-6, and IL-12p40 cytokines, whereas production of IL-2, IL-5 , IL-10, and IL-13 was decreased
Cominelli et al., Gastroenterology 1992 (Colitis) : Recombinant interleukin-1 receptor antagonist blocks the proinflammatory activity of endogenous interleukin-1 in rabbit immune colitis
Burger et al., J Clin Invest 1995 : The inhibitory activity of human interleukin-1 receptor antagonist is enhanced by type II interleukin-1 soluble receptor and hindered by type I interleukin-1 soluble receptor