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LPA — NUP43

Text-mined interactions from Literome

Moughal et al., J Neurochem 2006 : In contrast, the stimulation of PC12 cells with LPA leads to a predominant G ( i ) alpha2 mediated Trk A-independent activation of p42/p44 MAPK, where Gbetagamma subunits play a diminished role
Estrella et al., Int J Oncol 2007 (MAP Kinase Signaling System...) : LPA stimulation of ovarian cancer cells markedly increased the phosphorylation and activity of p38 ( MAPK ), p42/p44(MAPK) , and PI3K
Hurst et al., BMC neuroscience 2008 : LPA and S1P also induce p44/42 ERK MAP kinase phosphorylation in these cells and stimulate cell proliferation via G i/o coupled receptors in an Epidermal Growth Factor Receptor (EGFR)- and ERK dependent pathway
Gaits et al., Kidney Int 1997 (Glomerulonephritis, Membranoproliferative) : At 10 to 20 microM, LPA stimulated thymidine incorporation as well as phosphorylation of mitogen activated protein kinases ( MAP-kinases ) p42-p44 in dose- and time dependent manner, which demonstrated a positive effect on cell proliferation