Gene interactions and pathways from curated databases and text-mining

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MYLIP — RHOA

Text-mined interactions from Literome

Chiba et al., Am J Respir Crit Care Med 2009 (Asthma...) : Down-regulation of miR-133a contributes to up-regulation of Rhoa in bronchial smooth muscle cells ... To make clear the mechanism ( s ) of up-regulation of RhoA observed in the BSMs of experimental asthma, the role of miR-133a in RhoA expression was tested ... These findings suggest that RhoA expression is negatively regulated by miR-133a in BSMs. IL-13 might, at least in part, contribute to the reduction of miR-133a
Valastyan et al., Genes Dev 2011 (Breast Neoplasms...) : miR-31 triggers metastatic regression in the lungs by eliciting cell cycle arrest and apoptosis ; these responses occur specifically in metastases and can be explained by miR-31 mediated suppression of integrin-a5, radixin, and RhoA
Dagan et al., Blood 2012 (Lymphoma) : The effects of miR-155 on RhoA activation and cell motility can be rescued by transfection of HGAL lacking the miR-155 binding site
Yamamura et al., Carcinogenesis 2012 (Carcinoma, Renal Cell...) : miR-34a was also found to repress RhoA expression by suppressing the c-Myc-Skp2-Miz1 transcriptional complex that activates RhoA
Fan et al., Arthritis Rheum 2012 (Lupus Erythematosus, Systemic) : RhoA expression was directly repressed by miR-31 in T cells
Chang et al., Oral Oncol 2013 (Carcinoma, Squamous Cell...) : Passenger strand miRNA miR-31 ( * ) regulates the phenotypes of oral cancer cells by targeting RhoA
Huang et al., Int J Oncol 2013 (Lung Neoplasms...) : Overexpression of miR-125a-3p by transfection of sense-miR-125a-3p resulted in decreased RhoA protein levels, while the levels of RhoA mRNA remained constant