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CD79A — GRB2

Pathways - manually collected, often from reviews:

• BioCarta bcr signaling pathway: B-cell antigen/BCR/CD79A/CD79B/Btk/LYN/BLNK complex (BCR-CD79A-CD79B-BTK-LYN-BLNK) → SHC/GRB2/SOS-1 complex (SOS1-GRB2-SHC1) (modification, activates)
  
• Reactome Reaction: CD79A → GRB2 (reaction) Watanabe et al., Biochem Biophys Res Commun 2000, Engels et al., Eur J Immunol 2001, Kabak et al., Mol Cell Biol 2002, Chiu et al., EMBO J 2002, Oellerich et al., Mol Cell Proteomics 2009, Oellerich et al., EMBO J 2011, Fu et al., J Biol Chem 1997, Fu et al., Immunity 1998, Wienands et al., J Exp Med 1998
• Reactome Reaction: CD79A → GRB2 (indirect_complex) Watanabe et al., Biochem Biophys Res Commun 2000, Engels et al., Eur J Immunol 2001, Kabak et al., Mol Cell Biol 2002, Chiu et al., EMBO J 2002, Oellerich et al., Mol Cell Proteomics 2009, Oellerich et al., EMBO J 2011, Fu et al., J Biol Chem 1997, Fu et al., Immunity 1998, Wienands et al., J Exp Med 1998

Text-mined interactions from Literome

Harmer et al., J Biol Chem 1999 : Here, we report that cross linking of the BCR induces association between Grb2 and SHIP as well as association between Shc and SHIP
Ingham et al., J Biol Chem 2001 : Gab1 expression also increased BCR induced tyrosine phosphorylation of SHP2 as well as the binding of Grb2 to SHP2
Gaston et al., Exp Hematol 2004 : In a yeast three-hybrid assay, Grb2 mediated an interaction between Cbl and Bcr-Abl that was dependent on a functional Grb2 binding site ... Grb2 or another, yet unidentified, protein may mediate an initial interaction between Cbl and Bcr-Abl that is independent of Cbl tyrosine phosphorylation
Maru et al., Mol Cell Biol 1995 (Cell Transformation, Neoplastic) : Tyrosine phosphorylation of BCR by FPS/FES protein-tyrosine kinases induces association of BCR with GRB-2/SOS ... Tyrosine phosphorylation of BCR in v-fps transformed cells induced its association with GRB-2/SOS , the RAS guanine nucleotide exchange factor complex
Smit et al., Oncogene 1996 (Burkitt Lymphoma) : B-cell antigen receptor (BCR) stimulation induces tyrosine phosphorylation of the Shc adaptor protein and its association with Grb2 ... We reveal here an additional complexity of the BCR induced Shc/Grb2 complex : it contains tyrosine phosphorylated proteins of 130, 110 and 75 kDa