Gene interactions and pathways from curated databases and text-mining

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ADAM10 — ADAM21

Text-mined interactions from Literome

Peng et al., Neuroscience 2007 (Alzheimer Disease...) : Hup A enhanced the level of ADAM10 , and the inhibitor of tumor necrosis factor-alpha converting enzyme ( TACE ) /ADAM17 inhibited the Hup A-induced rise in alphaAPPs levels, further suggesting Hup A directed APP metabolism toward the non-amyloidogenic alpha-secretase pathway
Linford et al., Dev Cell 2012 : In FAM116A- and Rab14 depleted cells, ADAM10 accumulates in a transferrin positive endocytic compartment, and the cell-surface level of ADAM10 is correspondingly reduced