Cai et al., Nat Immunol 2008
:
Inhibition of CD4+ T cell activation by HVEM transfected cells was dependent on CD160 and BTLA ; when the cysteine-rich domain 1 of HVEM was deleted, this inhibition was lost, resulting in strong T cell activation
Xia et al., Molecular vision 2010
(Hypersensitivity, Delayed...) :
To investigate the effect of the B and T lymphocyte attenuator ( BTLA ; CD272 ) on cluster of differentiation (CD)4 ( + ) T cell mediated corneal immunopathology during murine herpetic stromal keratitis ( HSK ) ... BTLA expression increased both in the corneas of HSV-1 infected mice and in CD4 ( + ) T cells in the murine peripheral blood