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ANGPT2 — EDN1

Text-mined interactions from Literome

Kohno et al., Circ Res 1992 : Ang II dose-dependently stimulated immunoreactive endothelin-1 secretion
Luther et al., Endocrinology 2009 : Endogenous aldosterone contributes to the acute stimulatory effect of Ang II on PAI-1 and ppET-1 mRNA expression in the heart ; renin activity correlates with basal profibrotic gene expression in the kidney
Chao et al., J Nutr Biochem 2010 : Ang II increased fibroblast proliferation and endothelin-1 expression, which were partially inhibited by L-carnitine
Cheng et al., Anesthesiology 2010 : Ang II ( 100 nm ) increased cell proliferation and endothelin-1 expression, which were partially inhibited by propofol ( 10 or 30 microm )
Wolf et al., Hypertension 1996 : Ang II stimulated the synthesis and release of endothelin-1 in culture supernatants
Kudoh et al., Circ Res 1997 : Ang II increased transcription of the endothelin-1 gene through the AP-1 binding site
Spinale et al., Circulation 1997 (Disease Models, Animal...) : ACEI and AT1 Ang II blockade reduced LVEDD ( 4.68+/-0.07 cm ) and increased LVFS ( 25.2+/-0.9 % ) from pacing only ( P < .05 ). Plasma norepinephrine and endothelin increased by more than fivefold with chronic pacing and remained elevated with AT1 Ang II blockade. Plasma norepinephrine was reduced from pacing-only values by more than twofold in the ACEI group and the combination group. ACEI and AT1 Ang II receptor blockade reduced plasma endothelin levels by > 50 % from rapid pacing values