Gene interactions and pathways from curated databases and text-mining

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CCND1 — IL6

Text-mined interactions from Literome

Leclercq et al., Gastroenterology 2003 (Drug-Induced Liver Injury...) : Leptin replacement corrected these defects in ob/ob mice by restoring TNF and IL-6 release and inducing cyclin D1
Chen et al., Br J Pharmacol 2006 : Furthermore, Mag suppressed IL-6 induced promoter activity of cyclin D1 and monocyte chemotactic protein (MCP)-1 for which STAT3 activation plays a role
Wang et al., Circ Res 2007 (Carotid Artery Injuries...) : IL-6 also induced cyclin D1 expression in a time- and gp130/STAT-3 dependent manner in VSMCs. Suppression of cyclin D1 levels via the use of its small interfering RNA molecules inhibited IL-6 induced VSMC motility
Won et al., Anticancer Res 2010 (Carcinoma, Hepatocellular...) : CADPE significantly inhibited IL-6 induced signal transducer and activator of transcription 3 ( STAT3 ) activity in the Huh7 HCC cell line and attenuated IL-6 induced cyclin D1 transcription