Gene interactions and pathways from curated databases and text-mining

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CXCL12 — HGF

Text-mined interactions from Literome

Maroni et al., Carcinogenesis 2007 (Breast Neoplasms...) : HGF induces CXCR4 and CXCL12 mediated tumor invasion through Ets1 and NF-kappaB
Tu et al., Onkologie 2009 (Glioma...) : CXCR4 and SDF-1 production are stimulated by hepatocyte growth factor and promote glioma cell invasion ... In this study, we investigated the ability of HGF to promote the proliferation and invasion of U251n cells ; we also tested the effects of HGF on stromal cell derived factor 1 (SDF1) and CXCR4 mRNA expression
Tesio et al., Blood 2011 : Interestingly, stromal cell derived factor 1/CXC chemokine receptor-4 signaling induced hepatocyte growth factor production and c-Met activation